Profile of Larry J. Young

Larry.

Larry Abbott

Larry Abbott Columbia University Larry Abbott is the William Bloor Professor of Theoretical Neuroscience at Columbia University. He received his PhD in physics from Brandeis University in 1977 and worked in theoretical particle physics at the Stanford Linear Accelerator Center, at CERN (the European center for particle physics), and as a physics faculty member at Brandeis. Abbott began a transi...

Profile of David J. Mangelsdorf.

T wo decades ago, David Mangelsdorf did not expect his basic research findings to help launch an entire field of biology with farreaching implications for a raft of human diseases, including cancer, metabolic disorders, and parasitic infections. Mangelsdorf, a Howard Hughes Medical Institute investigator and a professor of pharmacology at the University of Texas Southwestern Medical Center at D...

Profile of Raymond J. Deshaies.

Protein homeostasis is crucial to the health of living cells, and dysregulated protein homeostasis can trigger diseases, including cancer. Biochemical cell biologist Raymond Deshaies has devoted his distinguished career to the analysis of protein homeostasis and the development of therapeutic approaches to counter diseases that result when homeostasis goes awry. Deshaies has served as a profess...

Profile of Scott J. Hultgren.

During her lifetime, an adult woman has a 50% chance of developing a urinary tract infection—one of the most common types of infections (1). Most urinary tract infections are caused by strains of the bacterium Escherichia coli, and, for the most part, are easily treated with antibiotics. However, many of these infections become chronic or recurrent because of increasing antibiotic resistance an...